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Long-Term Study Shows Stress Management Techniques Improve Mood and Quality of Life for Breast Cancer Patients

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Key Points

  • Depressive symptoms have been associated with neuroendocrine and inflammatory processes that may influence breast cancer progression.
  • Survivors in the longer stress management group reported levels of depression and quality of life at the 15-year follow-up that were similar to those reported by women without breast cancer.
  • The psychosocial support was equally helpful across different races and ethnic backgrounds.

A new study showed that providing women with skills to manage stress early in their breast cancer treatment can improve their mood and quality of life many years later. Published by Stagl et al in Cancer, the findings suggest that women given the opportunity to learn stress management techniques during treatment may benefit well into survivorship.

Study Details

In the year 2000, 240 women with a recent breast cancer diagnosis participated in a randomized trial that tested the effects of a stress management intervention developed by Michael Antoni, PhD, Professor of Psychology and Director of the Center for Psycho-Oncology Research at the University of Miami. Dr. Antoni and his team found that, compared with patients who received a 1-day seminar of education about breast cancer, patients who learned relaxation techniques and new coping skills in a supportive group over 10 weeks experienced improved quality of life and less depressive symptoms during their first year of treatment.

In their latest report, the researchers found that the women who received the stress management intervention had persistently less depressive symptoms and better quality of life up to 15 years later.

“Women with breast cancer who participated in the study initially used stress management techniques to cope with the challenges of primary treatment to lower distress. Because these stress management techniques also give women tools to cope with fears of recurrence and disease progression, the present results indicate that these skills can be used to reduce distress and depressed mood and optimize quality of life across the survivorship period as women get on with their lives,” said lead author Jamie Stagl, MS, Clinical Fellow in the Department of Psychiatry at Massachusetts General Hospital.

Long-Term Benefits

Ms. Stagl noted that breast cancer survivors in the longer stress management group reported levels of depression and quality of life at the 15-year follow-up that were similar to those reported by women without breast cancer. The intervention was equally helpful for women of various races and ethnic backgrounds. “This is key, given the fact that ethnic minority women experience poorer quality of life and outcomes after breast cancer treatment,” said Ms. Stagl.

As survival rates increase for breast cancer, the question of how to maintain psychosocial health becomes increasingly salient. The current findings highlight the possibility that psychologists and social workers may be able to help women, by providing them with stress management skills early in treatment to, hopefully, maintain long-term psychosocial health.

“Because depressive symptoms have been associated with neuroendocrine and inflammatory processes that may influence cancer progression, our work is ongoing. We are examining the effects of stress management on depression and inflammatory biomarkers on the one hand and disease recurrence and survival on the other,” said Dr. Antoni.

Dr. Antoni is the corresponding author of the Cancer article.

The content in this post has not been reviewed by the American Society of Clinical Oncology, Inc. (ASCO®) and does not necessarily reflect the ideas and opinions of ASCO®.


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