Advertisement

Search Results

Advertisement



Your search for Priscilla K. Brastianos, MD matches 7 pages

Showing 1 - 7


cns cancers
genomics/genetics

Focal Adhesion Kinase Inhibitor in Patients With Meningioma and Somatic NF2 Mutations

As reported in the Journal of Clinical Oncology by Priscilla K. Brastianos, MD, PhD, and colleagues, the phase II Alliance A071401 trial showed activity of the focal adhesion kinase (FAK) inhibitor GSK2256098 in patients with recurrent or progressive grade 1 to 3 meningioma and somatic NF2...

cns cancers
genomics/genetics

Deciphering the Elusive Origin and Pathways of Brain Metastases

The effective treatment of patients with brain metastases is an unmet need because, until fairly recently, patients with brain metastases were excluded from clinical trials of systemic therapies. However, the emergence of molecular targeted therapies has allowed a new treatment approach in patients ...

issues in oncology
genomics/genetics

Priscilla K. Brastianos, MD, on CNS Metastases: Understanding Their Evolution and the Clinical Implications

Priscilla K. Brastianos, MD, of Harvard Medical School and Massachusetts General Hospital, talks about her efforts to better understand how brain metastases evolve genomically and to test such agents as abemaciclib, paxalisib, and entrectinib, which may stop their growth. Palbociclib, a CDK...

cns cancers
immunotherapy

Two Studies Examine the Efficacy of Immunotherapy for Leptomeningeal Carcinomatosis

Two new studies published in Nature Communications indicate that immunotherapy may benefit people with leptomeningeal carcinomatosis, a rare but serious complication of cancer that has spread to the brain and/or spinal cord.  Approximately 5% to 8% of all patients with cancer develop leptomeningeal ...

Listen to Conquer Cancer Mini-Podcasts Inspired by StoryCorps and ASCO Members, Grantees

Debuting this year, “Your Stories: Conquering Cancer” are unscripted conversations among doctors, patients, and caregivers who have been affected by cancer.  The Conquer Cancer Foundation produced the mini-podcast series through the award-winning StoryCorps organization, a national nonprofit...

solid tumors
cns cancers

Priscilla K. Brastianos, MD, on Genetic Screening of Brain Metastases

Priscilla K. Brastianos, MD, of Massachusetts General Hospital, discusses genomic characterization of brain metastases and paired primary tumors, which could reveal potential therapeutic targets (Abstract 2905).

breast cancer

ASCO Guideline for Management of Brain Metastases From  HER2-Positive Breast Cancer: An Important Framework

Brain metastases are a devastating complication of cancer, and occur in up to 50% of patients with advanced human epidermal growth factor 2 (HER2)-positive breast cancer. Management of brain metastases requires individualized coordination between the traditional treatment modalities for...

Advertisement

Advertisement



Advertisement