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Make a Holiday Gift to Conquer Cancer,® the ASCO Foundation

Help fund breakthrough cancer research on behalf of someone you love this holiday season. Make a gift in honor or in memory of a loved one, and then send an e-card or mailed notification of your tribute. For many families, this time of year is marked by worry or grief rather than joy. With your...

Highlights From the 2019 ASCO Research Community Forum Annual Meeting

Researchers from around the country joined together for learning and collaboration at the 2019 ASCO Research Community Forum (RCF) Annual Meeting in September. During the meeting, Aisha Peterson Johnson, MD, MPH, MBA, of the U.S. Food and Drug Administration (FDA) Office of Compliance, delivered a...

Spotlight on Women Who Conquer Cancer

Women Who Conquer Cancer (WWCC) is a groundbreaking program that is committed to supporting early-career women researchers by funding research grants through Conquer Cancer®, the ASCO Foundation. Since its inception 6 years ago, the program has raised over $4 million, funded 21 Young Investigator...

CMS Finalizes Updates to E&M Codes, Establishes MIPS Value Pathways

The Centers for Medicare & Medicaid Services (CMS) released its final rule for the 2020 Medicare Physician Fee Schedule (MPFS) and other changes to Medicare Part B reimbursement policies, including proposals related to the Quality Payment Program (QPP). The estimated impact of the final MPFS...

ASCO and IASLC Collaborate to Improve the Quality of Lung Cancer Care in Brazil

Medical oncologists in Brazil are being encouraged to take advantage of a new measure set for assessing the quality of care they provide to patients with lung cancer. Lung cancer is one of the most prevalent and deadly types of cancer in Brazil.1 Providing a platform for health-care providers to...

V. Craig Jordan, PhD, DSc, Receives Award at Buckingham Palace

V. Craig Jordan, CMG, OBE, PhD, DSc, was presented with his Companion of the Most Distinguished Order of Saint Michael and Saint George (CMG) for services to women’s health.  Prince William presented the award on November 5. Dr. Jordan was recognized for his  discovery and development of selective...

multiple myeloma

Taking a Reasonable Approach to Treating Newly Diagnosed Multiple Myeloma

Multiple myeloma is a malignancy characterized by clonal proliferation of terminally differentiated plasma cells within the bone marrow. Although it leads to a host of different issues within the body, overall survival has steadily improved in recent years. “This is largely because of better...

lymphoma
immunotherapy

KEYNOTE-013 and KEYNOTE-170: Improving the Precision of Checkpoint Blockade in Patients With Diffuse Large B-Cell Lymphoma

Primary mediastinal B-cell lymphoma is an uncommon but distinct clinicopathologic variant of diffuse large B-cell lymphoma (DLBCL) that typically presents with an aggressive mediastinal mass and invasion of local structures. Most patients are young, typically in their 20s and 30s, and there is a...

Oncology Analytics Appoints Lee Newcomer, MD, as Strategic Advisor

Oncology Analytics, a technology-enabled service company that provides health plans, providers, and patients with an evidence-based, analytics-focused approach to utilization management, purpose-built for oncology, has announced the appointment of Lee Newcomer, MD, as a strategic advisor. Dr....

New Award and Grant to Support Pediatric Cancer Research

The American Association for Cancer Research (AACR) and the St. Baldrick’s Foundation announced the creation of the AACR–St. Baldrick’s Foundation Award for Outstanding Achievement in Pediatric Cancer Research. The award includes a grant to provide support for a junior faculty investigator to...

Leukemia & Lymphoma Society and ASH Team Up to Connect Patients With Blood Cancer to Clinical Trials

The Leukemia & Lymphoma Society (LLS) and the American Society of Hematology (ASH) recently announced a collaboration to expand access to LLS’s free service that provides clinical trials navigation and support to patients with hematologic malignancies and their families. With approximately 5%...

issues in oncology

Time to Treatment Is a Priority

Dr. Smith called us on a Tuesday afternoon. “I have a patient who has an abnormal mammogram showing a large mass. I’m suspecting cancer and am referring her to you for diagnosis and treatment. She’s very anxious. I hope you can help.” We were able to get Dr. Smith’s patient in the next day for...

Professor Jean-Charles Soria Appointed General Director of Gustave Roussy

In a statement from Gustave Roussy on December 16, 2019, the following news was released: “By an order, the Minister of Health and Solidarity, Madame Agnès Buzyn, appointed Professor Jean-Charles Soria as General Director of Gustave Roussy for a term of 5 years. He will assume his responsibilities...

Edmondo Robinson, MD, MBA, FACP, Joins Moffitt as Chief Digital Innovation Officer

Edmondo Robinson, MD, MBA, FACP, has joined Moffitt Cancer Center in Tampa as the new Senior Vice President and Chief Digital Innovation Officer. This newly created position will be critical to Moffitt’s success and navigating a continually evolving health-care industry. Dr. Robinson brings over...

multiple myeloma

My Dream Is That Multiple Myeloma Will One Day Be in My Past and No Longer a Part of My Future

A year before my diagnosis of multiple myeloma, in 2010, my husband Paul and I moved with our six children to Monterrey, Mexico, where Paul was helping to create a venture capital industry. We were so busy settling into a new country and getting our children integrated into school that when I...

lung cancer
bladder cancer
colorectal cancer
hematologic malignancies
myelodysplastic syndromes
breast cancer
head and neck cancer
immunotherapy

FDA Pipeline: Priority Reviews in SCLC, Bladder Cancer, Colorectal Cancer

Recently, the U.S. Food and Drug Administration (FDA) granted Priority Reviews for treatments in extensive-stage small cell lung cancer (SCLC), non–muscle invasive bladder cancer, and BRAF V600E–mutant colorectal cancer. The Agency also recently issued multiple Breakthrough Therapy designations and ...

Explaining Risk Factors Related to Anal Cancer

A recent study found rising rates of squamous cell carcinoma of the anus, “particularly advanced-stage disease, and a similar rise in mortality.”1 The authors concluded: “Improved prevention strategies are urgently needed to mitigate the rising [squamous cell carcinoma of the anus] burden among a...

breast cancer

FDA Approves Fam-Trastuzumab Deruxtecan-nxki for Patients With Unresectable or Metastatic HER2-Positive Breast Cancer

On December 20, the U.S. Food and Drug Administration (FDA) granted accelerated approval to fam-trastuzumab deruxtecan-nxki (Enhertu) for patients with unresectable or metastatic HER2-positive breast cancer who have received two or more prior anti–HER2-based regimens in the metastatic setting....

solid tumors

Incidence of Squamous Cell Carcinoma of the Anus Has ‘Increased Dramatically’ in Older Women and Young Black Men

“Squamous cell carcinoma of the anus incidence has increased dramatically in elderly women and young black men,” according to a study of recent trends in incidence and mortality. “Advanced-stage [anal squamous cell carcinoma] incidence tripled with a prominent rise in … mortality,” researchers...

issues in oncology

The Rise and Fall of Tobacco Products in the United States

It was a press conference on a cold Saturday in January 1964 that had garnered international attention, but the trappings were those of a secret government meeting, behind locked doors secured by uniformed guards. To the chagrin of the reporters, “no smoking” signs had been hastily posted around...

Dana-Farber Researcher Receives Victoria Mock New Investigator Award From ONS

Robert Knoerl, PhD, RN, an Instructor in Medicine and Nurse Scientist in the Phyllis F. Cantor Center for Research in Nursing and Patient Care Services at Dana-Farber Cancer Institute, has been awarded the 2020 Oncology Nursing Society’s Victoria Mock New Investigator Award. Dr. Knoerl was...

lung cancer

Global Survey Shows Misperceptions About Lung Cancer Among the General Public

Only one in five people (22%) disagrees with the statement “generally, patients with lung cancer have caused their illness through their lifestyle choices and behaviors,” according to a global, omnibus survey conducted by Ipsos MORI and sponsored by the Lung Ambition Alliance. The results were...

breast cancer

Companion Diagnostic Approved for Alpelisib/Fulvestrant Therapy

On December 4, the U.S. Food and Drug Administration (FDA) approved FoundationOne CDx to be used as a companion diagnostic for alpelisib in combination with fulvestrant for the treatment of postmenopausal women as well as male patients with hormone receptor–positive, HER2-negative, PIK3CA-mutated,...

American Cancer Society and Flatiron Health Launch Real-World Data Impact Award

The American Cancer Society (ACS) and Flatiron Health has announced the launch of the American Cancer Society & Flatiron Health Real-World Data Impact Award. This joint grant-making program supports both organizations’ goals of accelerating cancer research and improving treatment and care...

leukemia

Selected Abstracts From the 2019 ASH Annual Meeting & Exposition

To complement The ASCO Post’s comprehensive coverage of the 2019 American Society of Hematology (ASH) Annual Meeting & Exposition, here are several abstracts selected from the meeting proceedings focusing on novel therapeutic regimens for acute myeloid leukemia (AML). For full details of these...

lymphoma

The WHO Classification of Tumors of Hematopoietic and Lymphoid Tissues

The ASCO Post is pleased to present Hematology Expert Review, an ongoing feature that quizzes readers on issues in hematology. In this installment, Syed Ali Abutalib, MD, and L. Jeffrey Medeiros, MD, explore the updated World Health Organization (WHO) classification of hematopoietic and lymphoid ...

breast cancer

Mobile App Designed to Match Patients With Metastatic Breast Cancer With Clinical Trials

The Metastatic Breast Cancer Alliance (MBCA), the largest coalition of nonprofit breast cancer organizations, pharmaceutical/biotech companies, and patient advocates in the United States, recently announced the release of MBC Connect 2.0. MBC Connect is an interactive, Web- and mobile-friendly...

lung cancer

Long-Term Data on Brigatinib in First-Line Setting of ALK-Positive Non–Small Cell Lung Cancer

Updated data from the phase III ALTA-1L trial were presented by D. Ross Camidge, MD, PhD, of the University of Colorado Cancer Center, Aurora, during the Presidential Session at the European Society for Medical Oncology (ESMO) Asia Congress 2019 in Singapore.1 The trial evaluated brigatinib vs...

supportive care

Coexisting With Cancer and Depression

Among the highlights at the 2019 Supportive Care in Oncology Symposium in October was the keynote address by Thomas J. Smith, MD, FACP, FASCO, FAAHPM, the Harry J. Duffey Family Professor of Palliative Medicine and Director of Palliative Medicine at Johns Hopkins Medicine and Professor of Oncology ...

hematologic malignancies
symptom management

Expert Point of View: Preet M. Chaudhary, MD, PhD

Preet M. Chaudhary, MD, PhD, of the University of Southern California (USC) Keck School of Medicine, Los Angeles, commented on the HOVON-96 trial for The ASCO Post. Dr. Chaudhary is Professor and Chief of Hematology, the Ronald H. Bloom Family Chair in Lymphoma Research, and Program Director of...

skin cancer

ACCC Project Focuses on Multidisciplinary Care of Cutaneous Squamous Cell Carcinoma

Due to the rarity of advanced cutaneous squamous cell carcinoma, staying current with the latest information on diagnosing, treating, and supporting patients with this diagnosis can be challenging for clinicians who do not often encounter it in practice. To support the multi-disciplinary cancer...

New Cancer Center and Partnership With Sarah Cannon Cancer Institute at HCA Midwest Health

Golden Valley Memorial Healthcare, a leading rural health-care organization, is proud to announce its new cancer center and partnership with Sarah Cannon Cancer Institute at HCA Midwest Health, a leader in world-class cancer care, and HCA Midwest Health, Kansas City’s largest health network and...

J. Jack Lee, PhD, of MD Anderson Cancer Center Earns Election as AAAS Fellow

The University of Texas MD Anderson Cancer Center has announced that J. Jack Lee, PhD, has been named a Fellow in the American Association for the Advancement of Science (AAAS). Dr. Lee is Associate Vice President of Quantitative Sciences and Biostatistics at MD Anderson and a leader in the design ...

head and neck cancer
integrative oncology
symptom management

Acupuncture May Reduce Radiation-Induced Dry Mouth for Patients With Head and Neck Cancer

After receiving acupuncture treatment 3 days a week during the course of radiation treatment, patients with head and neck cancer experienced less dry mouth, according to study results published by Garcia et al in JAMA Network Open. The results are from the first randomized, placebo-controlled,...

Ashwani Rajput, MD, Named Director of Johns Hopkins Kimmel Cancer Center for Washington, DC, Region

Ashwani Rajput, MD, a surgical oncologist and researcher, has been appointed Director of the Kimmel Cancer Center at Johns Hopkins for the Washington, DC, region. Dr. Rajput assumed his new role in November 1 and is based at Sibley Memorial Hospital in Washington, DC. Dr. Rajput specializes in the ...

supportive care

ASCO/NCODA Release Standards for Medically Integrated Dispensing of Oral Anticancer Drugs

ASCO and the National Community Oncology Dispensing Association (NCODA) have published recommended standards for medically integrated dispensing of oral anticancer therapies and supportive care medications in the oncology clinic.1 “The NCODA created quality standards 6 years ago and recognized the ...

issues in oncology

ASCO’s National Cancer Opinion Survey Finds Gaps in Knowledge on Cancer Prevention and the Dangers of E-Cigarettes

As in the previous 2 years, the results from ASCO’s 2019 Cancer Opinion Survey revealed some startling answers about the public’s understanding of cancer, its risk factors, and strategies to prevent the disease. Although a majority of Americans (57%) said they were concerned about developing...

multiple myeloma

Relapsed or Refractory Multiple Myeloma Outcomes Improving Exponentially

Emerging treatments for relapsed or refractory multiple myeloma include options beyond triplet regimens, including immunotherapy and mutation-driven therapy. Several exciting drugs are poised to be available in the clinic in 2020, according to speakers at the recent JADPRO Live, the annual...

Expert Point of View: Thierry Facon, MD, and Michael Jain, MD, PhD

Thierry Facon, MD, Professor of Hematology at Lille University Hospital in France, and Michael Jain, MD, PhD, of Moffitt Cancer Center, Tampa, were interviewed by The ASCO Post on the second-generation chimeric antigen receptor (CAR) T-cell products for treating multiple myeloma. According to Dr. ...

immunotherapy
lung cancer

ESMO Immuno-Oncology 2019: Safety Analysis Results for First-Line Durvalumab Plus Platinum/Etoposide in Extensive-Stage SCLC

Few grade 3 or higher immune-related adverse events were observed in patients treated with first-line durvalumab plus platinum/etoposide for extensive-stage small cell lung cancer (SCLC), according to findings from the safety analysis of the phase III CASPIAN study presented by Özgüroğlu et al at...

bladder cancer

FDA Approves Enfortumab Vedotin-ejfv for Previously Treated Advanced Urothelial Cancer

On December 18, the U.S. Food and Drug Administration (FDA) granted accelerated approval to enfortumab vedotin-ejfv (Padcev) for adult patients with locally advanced or metastatic urothelial cancer who have previously received neoadjuvant or adjuvant treatment with a programmed cell death protein 1 ...

CancerCare to Provide Support for Patients With Cancer Impacted by the California Wildfires

As many California residents continue to deal with the aftermath of past wildfires and the advent of new ones, CancerCare is now offering a patient assistance program for both emotional and financial support to patients with cancer affected by the California fires. As a leading national nonprofit...

issues in oncology

How to Give Effective Presentation Feedback

Giving an effective scientific presentation, like all public speaking, is an acquired skill that takes practice to perfect. When delivered successfully, an oral presentation can be an invaluable opportunity to showcase your latest research results among your colleagues and peers. It can also...

skin cancer

ASTRO Issues Clinical Guideline on Radiation Therapy for Basal Cell and Cutaneous Squamous Cell Carcinomas

A new clinical guideline from the American Society for Radiation Oncology (ASTRO) provides recommendations on the use of radiation therapy to treat patients diagnosed with the most common types of skin cancers. The guideline details when radiation treatments are appropriate as stand-alone therapy...

symptom management

Single-Fraction vs Multifraction Radiotherapy for Patients With Spine Metastases

Spinal canal compression is a common complication in patients with cancer if disease metastasizes to the spine—about 3% to 5% of patients with cancer develop it. Radiotherapy is used to control pain and alleviate symptoms. According to results from the SCORAD randomized clinical trial, published by ...

colorectal cancer
head and neck cancer
pancreatic cancer

Early Research Shows Potential New Targets in Treating Glioblastoma, Colorectal Cancer, and Pancreatic Ductal Adenocarcinoma

Glioblastoma multiforme, colorectal cancer, and pancreatic ductal adenocarcinoma represent some of the most difficult-to-treat cancers and collectively cause more than 114,000 deaths each year in the United States. A trio of recently published basic research studies in these cancers have found...

issues in oncology
genomics/genetics

A Systematic Approach to Identifying the Molecular Factors That Lead to Cancer Progression

Although gene mutations are the primary drivers of carcinogenesis, an array of complex and tumor-specific molecular interaction networks determine cancer cell behavior. To learn more about this line of inquiry, The ASCO Post recently spoke with Andrea Califano, Dr., Professor of Chemical Biology...

issues in oncology

People With Mental Illness Receive Less Cancer Screening vs General Population

Results from a systematic review and comparative meta-analysis show that despite increased mortality from cancer in people with mental illness, this population receives less cancer screening compared to the general population. These findings were published by Solmi et al in The Lancet Psychiatry....

Everett E. Vokes, MD, FASCO, Elected ASCO President for 2021–2022 Term

ASCO membership has elected Everett E. Vokes, MD, FASCO, a long-time member and volunteer, to serve as its President for the 2021–2022 term. He will take office as President-Elect during the ASCO Annual Meeting in June 2020. Six new members were also elected to the ASCO Board of Directors and...

breast cancer

Study Links Sustained Weight Loss to Reduced Breast Cancer Risk

A new study finds that women who lost weight after age 50 and kept it off had a lower risk of breast cancer than women whose weight remained stable, helping answer a vexing question in cancer prevention.1 The reduction in risk increased with the amount of weight lost and was specific to women not...

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