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survivorship
issues in oncology

Cancer Survivors More Likely to Have Poor Diets Than Those With No History of Cancer

While most cancer survivors in the United States are motivated to seek information about food choices and dietary changes to improve their health, a new study comparing their dietary patterns to federal guidelines indicates that they often fall short. By Zhang et al in Cancer, the findings point to ...

breast cancer
survivorship
issues in oncology

ECC 2015: Treatment of Elderly Patients With Breast Cancer Varies Throughout Europe

First results from the largest international comparison of the treatment of elderly patients with breast cancer have shown substantial differences in the use of surgery, hormone therapy, and chemotherapy among European countries. The European Registration of Cancer Care (EURECCA) study compared the ...

survivorship

Tailored Education Improves Awareness of Risk for Therapy-Related Complications Among Childhood Cancer Survivors

In a study reported in the Journal of Clinical Oncology, Landier et al found that education tailored to personal risk for therapy-related complications improved risk awareness in survivors of childhood cancer. The level of awareness appeared to reach a maximum after several educational sessions....

breast cancer
survivorship
issues in oncology

ECC 2015: Hormone Therapy May Prevent Ovarian Failure and Preserve Fertility in Women With Breast Cancer

Young women undergoing chemotherapy for breast cancer may be more likely to remain fertile if they also receive hormonal treatment, according to new research (Abstract 1957) presented at the 2015 European Cancer Congress in Vienna, Austria, and published simultaneously by Lambertini et al in Annals ...

health-care policy
survivorship
issues in oncology
issues in oncology
issues in oncology

ECC 2015: Childhood Cancers in Europe: Progress Has Been Made, but Much Still to Do

Each year in Europe, 6,000 young people die from cancer, and two-thirds of those who survive suffer from treatment-related side effects. Although there has been considerable progress in the treatment of childhood cancers over the past few decades, and cancer in childhood is rare, these are major...

head and neck cancer
survivorship

ECC 2015: Association Between Primary Surgery and Survival Benefit in Patients With Advanced Throat Cancers

Patients with cancers of the mid and lower throat may have higher survival rates if their initial treatment includes surgery, according to new research (Abstract 2804) presented at the 2015 European Cancer Congress in Vienna, Austria. Researchers explained that a nationwide study in Taiwan found...

survivorship
issues in oncology
issues in oncology

ECC 2015: EUROCARE Results Show Large Variations in Survival Among European Countries

Comparisons of cancer patients’ survival and care in Europe up to 2007 showed that although more patients are surviving for at least 5 years after diagnosis, there are large variations among countries, which are particularly significant in cancers of the blood. Milena Sant, MD, from the...

survivorship

ASCO Statement: Recommendations for Obesity Clinical Trials in Cancer Survivors

As reported in the Journal of Clinical Oncology by Ligibel et al, ASCO has issued a statement providing recommendations for obesity clinical trials in cancer survivors. ASCO convened the Research Summit on Advancing Obesity Clinical Trials in Cancer Survivors in November 2014. The meeting involved...

breast cancer
issues in oncology
survivorship

Breast Cancer Symposium: Recurrence Rates for Ductal Carcinoma in Situ Treated Between 1978–2010

A new retrospective analysis explored local recurrence rates for women with ductal carcinoma in situ (DCIS) treated between 1978 and 2010. In the research (Abstract 32) by Van Zee et al, to be presented September 25 at the 2015 Breast Cancer Symposium, in San Francisco, investigators evaluated a...

skin cancer
issues in oncology
survivorship
issues in oncology
issues in oncology

Antifungal Agent Increases Risk of Cutaneous Squamous Cell Carcinoma in Some Lung Transplant Recipients

Voriconazole, commonly used to prevent and treat fungal infections in lung transplant recipients, significantly increases the risk for cutaneous squamous cell carcinoma in this population, according to a new study by University of California San Francisco researchers. The team recommends physicians ...

breast cancer
survivorship

Group-Based Behavioral Weight Loss Intervention Successful in Overweight/Obese Breast Cancer Survivors

Obesity increases the risk for overall and breast cancer mortality and comorbidity. As reported in the Journal of Clinical Oncology by Rock et al, the Exercise and Nutrition to Enhance Recovery and Good Health for You (ENERGY) study has shown that a group-based behavioral intervention can produce...

issues in oncology
survivorship
cost of care

AACR’s Cancer Progress Report Details Major Advances in Cancer and Rising Costs of Treatment

The American Association for Cancer Research (AACR) 2015 Cancer Progress Report highlighted the accelerated pace of the number of U.S. Food and Drug Administration (FDA)-approved targeted therapies over the past 5 years, which reached 52 this year; the dramatic increase in the 5-year survival rate...

survivorship

Dose Equivalence Analysis Indicates Reduced Risk of Late Heart Failure With Daunorubicin vs Doxorubicin in Survivors of Childhood Cancer

In a study reported in the Journal of Clinical Oncology, Feijen et al found that daunorubicin may be associated with reduced risk of late heart failure vs doxorubicin in survivors of childhood cancer. Study Details The study included data from 15,815 survivors of childhood cancer who survived...

breast cancer
supportive care
survivorship
issues in oncology

Sham and Real Electroacupuncture Reduce Hot Flashes vs Gabapentin and Pill Placebo in Breast Cancer Survivors

In a study assessing placebo effects reported in the Journal of Clinical Oncology, Mao et al found that sham electroacupuncture produced a greater reduction in hot flashes than placebo pills and gabapentin, with the greatest reduction being achieved with real electroacupuncture. Study Details In...

survivorship

Survivors of Childhood Cancer Have High Risk of Recurrent Stroke

Recent evidence suggests that survivors of childhood cancer have a high risk of suffering a stroke at a surprisingly young age. A new study from the UC San Francisco Pediatric Brain Center shows that childhood cancer survivors suffering one stroke have double the risk of suffering a second stroke...

survivorship

Increased Risk of Cancers After Age 40 in Childhood Cancer Survivors

In an analysis from the Childhood Cancer Survivor Study reported in the Journal of Clinical Oncology, Turcotte et al found that survivors of childhood cancer are at increased risk of subsequent malignant neoplasms after age 40 years. Study Details The study involved data from 3,171 survivors of...

survivorship

Increased Risk of Intestinal Obstruction and Mortality in Survivors of Childhood Cancer

As reported by Madenci et al in the Journal of Clinical Oncology, an analysis from the Childhood Cancer Survivor Study showed that childhood cancer survivors are at increased risk of intestinal obstruction requiring surgery at ≥ 5 years after cancer diagnosis and poorer overall survival. Study...

breast cancer
supportive care
survivorship
issues in oncology
issues in oncology

Fertility Concerns and Side Effects Keep Many Young Women With Breast Cancer From Taking or Completing Tamoxifen

Concerns about fertility kept one-third of young women with breast cancer surveyed in a recent study from taking tamoxifen, despite its known benefit in reducing the risk of breast cancer recurrence. In addition, the study found fertility concerns led one-quarter of women who started...

gynecologic cancers
gynecologic cancers
survivorship

Long-Term Survival in Ovarian Cancer May Be Better Than Expected in Some Patients

Combing data collected on thousands of California patients with ovarian cancer, University of California Davis researchers have determined that almost one-third of patients survived at least 10 years after diagnosis. The findings upend the notion that women diagnosed with cancer of the ovaries...

survivorship

Psychosocial and Neurocognitive Impairment in Adult Survivors of Adolescent and Young Adult Cancer

In an analysis from the Childhood Cancer Survivor Study reported in the Journal of Clinical Oncology, Prasad et al found evidence of impaired psychosocial and neurocognitive function among long-term cancer survivors diagnosed during adolescence and young adulthood. Risk of Impairment In the...

breast cancer
survivorship

Study Finds Breast Cancer Survivors Gain More Weight Than Cancer-Free Women

A prospective study examining weight gain in breast cancer survivors compared with cancer-free women from a familial risk cohort has found that, overall, breast cancer survivors gained significantly more weight than cancer-free women of the same age and menopausal status. According to the study...

pancreatic cancer
survivorship

National Cancer Database Analysis Identifies Characteristics of 10-Year Survivors of Pancreatic Ductal Adenocarcinoma

In an analysis reported in JAMA Surgery, Paniccia et al identified patient and treatment characteristics that were associated with survival of at least 10 years after diagnosis of invasive pancreatic ductal adenocarcinoma, including lower positive lymph node ratio, receipt of adjuvant chemotherapy, ...

leukemia
lymphoma
survivorship

Long-Term Follow-Up Suggests No Detrimental Survival Effect of Dexrazoxane in Pediatric Patients With Leukemia or Lymphoma

In an analysis of Children’s Oncology Group (COG) trials reported in the Journal of Clinical Oncology, Chow et al found that dexrazoxane use did not appear to be associated with poorer survival among pediatric patients with leukemia or lymphoma in long-term follow-up. Study Details The...

survivorship

ASCO 2015: Economic Costs a Burden for Cancer Survivors

A new study conducted by the American Cancer Society found that the economic burden of cancer extends beyond diagnosis and treatment, with cancer survivors facing thousands of dollars of excess medical expenses every year, as well as excess employment disability and loss of production at work. The...

survivorship

ASCO 2015: For Patients With Limited Brain Metastases, Adjuvant Whole-Brain Radiation Therapy Increases Cognitive Decline Without Improving Survival

A federally funded phase III trial found that adding whole-brain radiation therapy to radiosurgery did not significantly extend survival of patients with one to three small metastases of the brain, although it did help to control the growth of brain metastases, as evidenced by imaging studies....

leukemia
lymphoma
survivorship

ASCO 2015: Reduction in Late Mortality Among Childhood Cancer Survivors Linked to Improvements in Cancer Care

Survivors of childhood cancer in recent eras have shown a significant reduction in late mortality, and “for the first time, we have been able to attribute that to fewer deaths from treatment-related causes or fewer deaths from late effects of the primary therapy,” Gregory T....

survivorship
issues in oncology

AUA 2015: Sperm Banking Rates Increase With Fertility Counseling for Cancer Patients

Fertility counseling for men with cancer, prior to initiating treatment, can increase the rate of sperm preservation, according to a new survey by Rotker et al presented during the 110th Annual Scientific Meeting of the American Urological Association (AUA; Abstract PD52-11). Chemotherapy can...

survivorship
issues in oncology
issues in oncology
issues in oncology

Certain Treatments for Childhood Cancer May Increase Obesity Risk Later in Life

Individuals who had cancer as a child may be at increased risk of being obese due to the therapies they received during their youth. The finding comes from a new study published early by Wilson et al in Cancer. The study’s results suggest the need for effective counseling and weight loss...

survivorship

Increased Risk of Long-Term Pulmonary Dysfunction in Survivors of Childhood Cancer Who Received Pulmonary Toxic Treatments

In a single-center study reported in the Journal of Clinical Oncology, Armenian et al found that childhood cancer survivors who had received potentially pulmonary toxic treatment were at a significantly increased risk of long-term pulmonary dysfunction compared with healthy controls. Study Details ...

lymphoma
survivorship

Good Prognosis for Parenthood for Women Treated for Hodgkin Lymphoma During Childhood or Adolescence

In a German study reported in The Lancet Oncology, Brämswig et al found that women treated for Hodgkin lymphoma during childhood or adolescence had a good prognosis for achieving parenthood. Study Details This prospective longitudinal study included 467 female patients aged < 18 years at...

lymphoma
survivorship

Increased Lifetime Risk of Cardiovascular Disease for Patients Treated for Hodgkin Lymphoma as Adolescents or Adults

Survivors of Hodgkin lymphoma treated as adolescents or adults are at increased risk of cardiovascular disease throughout their lives, according to results of a retrospective cohort study of 2,524 Dutch patients followed for a median of 20 years. “Treating physicians and patients should be...

survivorship
issues in oncology
issues in oncology

Childhood Cancer Survivors More Likely to Claim Social Security Support as Adults

Today, more than 80% of childhood cancer patients survive because of advances in treatment and care. However, recent studies have shown that some of these more than 420,000 United States childhood cancer survivors face future health-related challenges as they become adults such as a second cancer...

lymphoma
survivorship

Excessive All-Cause and Second Primary Malignancy-Related Mortality and Frequent Late Morbidity in Hodgkin Lymphoma Patients Treated During Adulthood

In a single-institution study reported in the Journal of the National Cancer Institute, Matasar et al found that Hodgkin lymphoma patients treated during adulthood were at increased risk of all-cause and second primary malignancy mortality compared with SEER (Surveillance, Epidemiology, and...

colorectal cancer
prostate cancer
survivorship
issues in oncology

Physical Activity Helps Cancer Survivors Fend Off Side Effects

Three or more hours of walking per week can boost the vitality and health of prostate cancer survivors. Men and women who have survived colorectal cancer and are regular walkers also reported lower sensations of burning, numbness, tingling, or loss of reflexes that many often experience after...

breast cancer
supportive care
survivorship
issues in oncology

Long-Term Study Shows Stress Management Techniques Improve Mood and Quality of Life for Breast Cancer Patients

A new study showed that providing women with skills to manage stress early in their breast cancer treatment can improve their mood and quality of life many years later. Published by Stagl et al in Cancer, the findings suggest that women given the opportunity to learn stress management techniques...

issues in oncology
survivorship
issues in oncology

Cancer Patients Lack Knowledge but Desire More Information on Radiation-Based Medical Imaging Tests

A substantial gap exists between patient expectations and current practices for providing information about medical imaging tests that use radiation, according to a new study published by Thornton et al in the journal Radiology. Researchers said the findings highlight a need for better...

breast cancer
survivorship
issues in oncology

New Study Reveals Effective Treatment Program for Breast Cancer Survivors With ‘Chemobrain’

In a new study, UCLA researchers have developed a cognitive rehabilitation program to address post-treatment cognitive changes, sometimes known as “chemobrain,” which can affect up to 35% of post-treatment breast cancer patients. Their findings were reported by Erocli et al in...

survivorship

Study Finds Both the Number of Childhood Cancer Survivors and the Prevalence of Morbidity Are Increasing

Researchers investigating the prevalence of childhood cancer survivors and the population-level burden of morbidity in these survivors have found that although the number of childhood cancer survivors has increased by nearly 60,000 since 2005, the majority of those who have survived 5 or more years ...

survivorship

Survivors of Childhood Cancer at Risk for Developing Hormone Deficiencies as Adults

Decades after undergoing cranial irradiation for childhood cancer, St. Jude Children's Research Hospital investigators found that adult survivors of pediatric cancer remain at risk for pituitary hormone deficiencies, which may diminish their health and quality of life. Chemaitilly et al published...

survivorship

Poor Health Status More Common Among Childhood Cancer Survivors vs Siblings, With Age‑Related Increase in Prevalence

In a study in the Childhood Cancer Survivor Cohort reported in the Journal of Clinical Oncology, Hudson et al found that poor health status was more common in survivors than in siblings, with an age-related increase in prevalence particularly evident in female survivors. In the study, 22,568...

survivorship

Many Cancer Survivors Have Unmet Physical and Mental Needs Related to Their Disease and Its Treatment

Even decades after being cured, many cancer survivors face physical and mental challenges resulting from their disease and its treatment, according to a new study reported by Burg et al in Cancer. The findings could help clinicians and other experts develop interventions that are tailored to the...

breast cancer
supportive care
survivorship

Low-Level Laser Therapy May Reduce Limb Volume and Pain in Patients With Breast Cancer–Related Lymphedema

In a meta-analysis of patients with breast cancer–related lymphedema, low-level laser therapy was associated with reduced limb volume and pain levels, according to a report by Smoot et al in the Journal of Cancer Survivorship. However, the investigators noted that regarding pain management,...

leukemia
survivorship

ASH 2014: Common Genetic Variations May Contribute to Treatment-Related Cognitive Problems in Children With Leukemia

Common variations in four genes related to brain inflammation or cells′ response to damage from oxidation may contribute to the problems with memory, learning, and other cognitive functions seen in children treated for acute lymphoblastic leukemia (ALL), according to a study presented at the...

survivorship

Adult Survivors of Retinoblastoma Experience Few Cognitive or Social Setbacks

Adult survivors of retinoblastoma, a type of eye cancer that usually develops in early childhood, have few cognitive or social problems decades following their diagnosis and treatment, according to a study by Brinkman et al published in Cancer. The findings offer good news for patients, but the...

issues in oncology
survivorship

Advanced-Practice Nurse Telephone Counseling Improves Rate of Cardiomyopathy Screening in At‑Risk Adult Survivors of Pediatric Cancer

In the ECHOS trial reported in the Journal of Clinical Oncology, Hudson et al found that the addition of two tailored telephone counseling sessions by an advanced-practice nurse to a mailed personalized survivorship care plan including cardiac screening recommendations resulted in a greater than...

lymphoma
survivorship

Vigorous Exercise Lowers Risk of Cardiovascular Events in Adult Survivors of Childhood Hodgkin Lymphoma

In a report from the Childhood Cancer Survivor Study published in the Journal of Clinical Oncology, Jones and colleagues found that vigorous exercise reduces the risk of major cardiovascular events in adult survivors of childhood Hodgkin lymphoma. Study Details In the study, 1,187 survivors of...

survivorship

Scoring to Predict Individual Risk of Heart Failure Among Childhood Cancer Survivors

In a study reported in the Journal of Clinical Oncology, Chow and colleagues developed risk scoring that can identify likelihood of heart failure among childhood cancer survivors. Study Details The study involved survivors in the Childhood Cancer Survivor Study (CCSS) free of significant...

breast cancer
survivorship

Chest Radiation to Treat Childhood Cancer Increases Patients’ Risk of Developing Breast Cancer

A new study has found that patients who received chest radiation for Wilms tumor, a rare childhood cancer, face an increased risk of developing breast cancer later in life due to their radiation exposure. Reported by Lange et al in Cancer, the findings suggest that cancer screening guidelines might ...

survivorship

Higher Alkylating Agent Exposure Associated With Impaired Spermatogenesis in Adult Survivors of Childhood Cancer

In a study in the St. Jude Lifetime Cohort Study population reported in The Lancet Oncology, Green et al found that increasing alkylating agent exposure was associated with impaired spermatogenesis in adult male survivors of childhood cancer who did not undergo radiation therapy as part of their...

survivorship

One-Third of U.S. Cancer Survivors May Be Experiencing Financial or Work-Related Hardship

New results from a survey of nearly 1,600 cancer survivors indicate a high prevalence of financial and work-related difficulties: 27% reported at least one financial problem (eg, debt, bankruptcy), and 37% reported having to modify work plans, such as taking extended time off or delaying...

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